Michaelis-Gutmann bodies are small, circular or ovoid structures that are found in the cytoplasm of certain cells. They are composed of amorphous, dark-staining material and are often surrounded by a clear halo.
Michaelis-Gutmann bodies are typically found in cells that have been damaged by inflammation or other processes, such as certain types of cancer. They are named after two German pathologists, Adolf Michaelis and Wilhelm Gutmann, who described them in the early 20th century.
The presence of Michaelis-Gutmann bodies is often used as an indicator of the presence or progression of certain diseases, such as breast cancer and prostate cancer. They may also be used as a marker for certain types of infections, such as tuberculosis.
Further testing, such as microscopy or biopsy, is usually needed to confirm the presence and significance of Michaelis-Gutmann bodies in a given situation.